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Ligand · 0S7

0S7 · 5-bromo-N~4~-(3-methyl-1H-pyrazol-5-yl)-N~2~-[2-(pyridin-3-yl)ethyl]pyrimidine-2,4-diamine

0S7, 5-bromo-N~4~-(3-methyl-1H-pyrazol-5-yl)-N~2~-[2-(pyridin-3-yl)ethyl]pyrimidine-2,4-diamine (C15 H16 Br N7, 374.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
0S7
Formula
C15 H16 Br N7
Class
ligand
Structures
2
PDB entries
1

Binding sites

0S7 in 2 structures; the first of them:

  • 4F63 · Crystal structure of Human Fibroblast Growth Factor Receptor 1 Kinase domain in complex… · 0S7 A801 · binds LEU484, GLY485, VAL492, ALA512, LYS514, ILE545, VAL561, GLU562 and 8 more
  • 4F63 · Crystal structure of human fibroblast growth factor receptor 1 kinase domain in complex… · 0S7 A801 · binds LEU484, GLY485, VAL492, ALA512, LYS514, ILE545, VAL561, GLU562 and 8 more

Residues it binds most

ALA 4, GLY 4, LEU 4, VAL 4, ASP 4, GLU 4, ILE 4, LYS 2, SER 4, TYR 4 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

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