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Ligand · 0R4

0R4 · N-(4-{5-[3-(acetylamino)phenyl]-2-(2-aminopyridin-3-yl)-3H-imidazo[4,5-b]pyridin-3-yl}benzyl)-3-fluorobenzamide

0R4, N-(4-{5-[3-(acetylamino)phenyl]-2-(2-aminopyridin-3-yl)-3H-imidazo[4,5-b]pyridin-3-yl}benzyl)-3-fluorobenzamide (C33 H26 F N7 O2, 571.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
0R4
Formula
C33 H26 F N7 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

0R4 in 2 structures; the first of them:

  • 4EJN · Crystal structure of autoinhibited form of AKT1 in complex with… · 0R4 A501 · binds ASN53, ASN54, PHE55, GLN59, LEU78, GLN79, TRP80, THR82 and 13 more
  • 4EJN · Crystal structure of autoinhibited form of AKT1 in complex with N-(4… · 0R4 A501 · binds ASN53, ASN54, PHE55, GLN59, LEU78, GLN79, TRP80, THR82 and 13 more

Residues it binds most

LEU 2, THR 2, ASN 2, ASP 2, GLN 2, ILE 2, TYR 2, VAL 2, ARG 2, PHE 2 (residue and the binding sites it lines).

Found with

  • SBT · 2-butanol
  • EDO · 1,2-ethanediol

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