GL1X · GenesisL1 explorer

Ligand · 0QB

0QB · (2S)-2-[(2-amino-1,3-thiazol-4-yl)methyl]-N~1~-{(1S,2S)-1-(cyclohexylmethyl)-2-hydroxy-2-[(3R)-1,5,5-trimethyl-2-oxopyrrolidin-3-yl]ethyl}-N~4~-[2-(dimethylamino)-2-oxoethyl]-N~4~-[(1S)-1-phenylethyl]butanediamide

0QB, (2S)-2-[(2-amino-1,3-thiazol-4-yl)methyl]-N~1~-{(1S,2S)-1-(cyclohexylmethyl)-2-hydroxy-2-[(3R)-1,5,5-trimethyl-2-oxopyrrolidin-3-yl]ethyl}-N~4~-[2-(dimethylamino)-2-oxoethyl]-N~4~-[(1S)-1-phenylethyl]butanediamide (C36 H54 N6 O5 S…

Component
0QB
Formula
C36 H54 N6 O5 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

0QB in 2 structures; the first of them:

  • 1BIM · Crystallographic studies on the binding modes of P2-P3 butanediamide renin inhibitors · 0QB A391 · binds THR12, GLN13, VAL30, ASP32, GLY34, SER35, TYR75, SER76 and 19 more
  • 1BIM · Crystallographic studies on the binding modes of P2-P3 butanediamide renin inhibitors · 0QB A391 · binds THR12, GLN13, VAL30, ASP32, GLY34, SER35, TYR75, SER76 and 19 more

Residues it binds most

SER 4, ALA 4, THR 4, ASP 4, GLY 4, ILE 4, LEU 4, PHE 4, TYR 4, VAL 4 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.