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Ligand · 0Q5

0Q5 · 4-[5-butyl-3-(hydroxymethyl)-1-phenyl-1H-pyrazol-4-yl]-3-(3,4-dihydroisoquinolin-2(1H)-ylcarbonyl)-N-{[2-(trimethylsilyl)ethyl]sulfonyl}benzamide

0Q5, 4-[5-butyl-3-(hydroxymethyl)-1-phenyl-1H-pyrazol-4-yl]-3-(3,4-dihydroisoquinolin-2(1H)-ylcarbonyl)-N-{[2-(trimethylsilyl)ethyl]sulfonyl}benzamide (C36 H44 N4 O5 S Si, 672.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2…

Component
0Q5
Formula
C36 H44 N4 O5 S Si
Class
ligand
Structures
2
PDB entries
1

Binding sites

0Q5 in 2 structures; the first of them:

  • 4EHR · Crystal structure of Bcl-Xl complex with 4-(5-butyl-3-(hydroxymethyl)-1-phenyl-1h-pyrazol… · 0Q5 A301 · binds ALA93, GLU96, PHE97, ARG100, TYR101, ALA104, PHE105, LEU108 and 9 more
  • 4EHR · Crystal structure of BCL-xl complex with 4-(5-butyl-3-(hydroxymethyl)… · 0Q5 A301 · binds ALA93, GLU96, PHE97, ARG100, TYR101, ALA104, PHE105, LEU108 and 9 more

Residues it binds most

ALA 2, PHE 2, ARG 2, GLU 2, LEU 2, TYR 2, VAL 2, GLY 2 (residue and the binding sites it lines).

Found with

  • IMD · Imidazole

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