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Ligand · 0P6

0P6 · 2-aminoquinolin-8-ol

0P6, 2-aminoquinolin-8-ol (C9 H8 N2 O, 160.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
0P6
Formula
C9 H8 N2 O
Class
ligand
Structures
4
PDB entries
2

Binding sites

0P6 in 4 structures; the first of them:

  • 4EG8 · Trypanosoma brucei methionyl-tRNA synthetase in complex with compound Chem 89 · 0P6 B812 · binds TYR250, ASP287, HIS289, GLY290, GLU368, LEU456, ALA460, VAL471 and 4 more
  • 4YRC · Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with… · 0P6 A502 · binds ILE106, PRO125, CYS154, TRP155, ARG156, ARG165, ARG166, GLU167 and 1 more
  • 4EG8 · Trypanosoma brucei methionyl-tRNA synthetase in complex with compound chem 89 · 0P6 B812 · binds TYR250, ASP287, HIS289, GLY290, GLU368, LEU456, ALA460, VAL471 and 4 more
  • 4YRC · Crystal structure of T. cruzi histidyl-tRNA synthetase in complex with… · 0P6 A502 · binds ILE106, PRO125, CYS154, TRP155, ARG156, ARG165, ARG166, GLU167 and 1 more

Residues it binds most

VAL 4, ARG 4, ALA 4, ASP 2, GLU 4, GLY 4, HIS 4, PRO 4, TYR 2, CYS 2 (residue and the binding sites it lines).

Found with

  • DMS · Dimethyl sulfoxide
  • HIS · Histidine
  • MET · Methionine
  • SO4 · Sulfate ion
  • EDO · 1,2-ethanediol
  • GOL · Glycerol

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