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Ligand · 0NV

0NV · 1-(1-benzylpiperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine

0NV, 1-(1-benzylpiperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine (C20 H21 N5, 331.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
0NV
Formula
C20 H21 N5
Class
ligand
Structures
2
PDB entries
1

Binding sites

0NV in 2 structures; the first of them:

  • 4E6Q · JAK2 kinase (JH1 domain) triple mutant in complex with compound 12 · 0NV A1201 · binds LEU855, GLY856, LYS857, GLY858, GLY861, SER862, VAL863, ALA880 and 14 more
  • 4E6Q · JAK2 kinase (JH1 domain) triple mutant in complex with compound 12 · 0NV A1201 · binds LEU855, GLY856, LYS857, GLY858, GLY861, SER862, VAL863, ALA880 and 14 more

Residues it binds most

GLY 4, LEU 4, LYS 4, SER 4, VAL 4, GLU 4, ALA 4, ARG 4, ASN 4, ASP 4 (residue and the binding sites it lines).

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