GL1X · GenesisL1 explorer

Ligand · 0NT

0NT · [4-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl)piperidin-1-yl][(2S)-1-(propan-2-yl)pyrrolidin-2-yl]methanone

0NT, [4-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl)piperidin-1-yl][(2S)-1-(propan-2-yl)pyrrolidin-2-yl]methanone (C21 H28 N6 O, 380.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
0NT
Formula
C21 H28 N6 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

0NT in 2 structures; the first of them:

  • 4E5W · JAK1 kinase (JH1 domain) in complex with compound 26 · 0NT A1201 · binds LEU881, GLY882, GLU883, GLY884, VAL889, ALA906, VAL938, MET956 and 12 more
  • 4E5W · JAK1 kinase (JH1 domain) in complex with compound 26 · 0NT A1201 · binds LEU881, GLY882, GLU883, GLY884, VAL889, ALA906, VAL938, MET956 and 12 more

Residues it binds most

GLY 4, GLU 4, LEU 4, ASP 4, VAL 4, ALA 4, ARG 4, ASN 4, MET 4, PHE 4 (residue and the binding sites it lines).

Found with

  • PEG · Di(hydroxyethyl)ether

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.