GL1X · GenesisL1 explorer

Ligand · 0K0

0K0 · 3-amino-6-{3-[(methylsulfonyl)amino]phenyl}-N-(piperidin-4-ylmethyl)pyrazine-2-carboxamide

0K0, 3-amino-6-{3-[(methylsulfonyl)amino]phenyl}-N-(piperidin-4-ylmethyl)pyrazine-2-carboxamide (C18 H24 N6 O3 S, 404.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
0K0
Formula
C18 H24 N6 O3 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

0K0 in 2 structures; the first of them:

  • 4DFL · Crystal structure of spleen tyrosine kinase complexed with a sulfonamidopyrazine… · 0K0 A701 · binds LEU377, GLY378, SER379, VAL385, ALA400, VAL433, MET448, GLU449 and 10 more
  • 4DFL · Crystal structure of spleen tyrosine kinase complexed with a sulfonamidopyrazine… · 0K0 A701 · binds LEU377, GLY378, SER379, VAL385, ALA400, VAL433, MET448, GLU449 and 10 more

Residues it binds most

ALA 2, GLY 2, LEU 2, MET 2, SER 2, VAL 2, ARG 2, ASN 2, ASP 2, GLU 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • EDO · 1,2-ethanediol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.