GL1X · GenesisL1 explorer

Ligand · 0I1

0I1 · (3-fluoroazetidin-1-yl){1-[4-(4-fluorophenyl)pyrimidin-5-yl]piperidin-4-yl}methanone

0I1, (3-fluoroazetidin-1-yl){1-[4-(4-fluorophenyl)pyrimidin-5-yl]piperidin-4-yl}methanone (C19 H20 F2 N4 O, 358.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within…

Component
0I1
Formula
C19 H20 F2 N4 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

0I1 in 2 structures; the first of them:

  • 7N6F · Co-complex CYP46A1 with compound 3f · 0I1 A502 · binds PHE80, MET108, TYR109, LEU112, PHE121, VAL126, LEU219, ILE222 and 13 more
  • 7N6F · Co-complex CYP46A1 with compound 3F · 0I1 A502 · binds PHE80, MET108, TYR109, LEU112, PHE121, VAL126, LEU219, ILE222 and 11 more

Residues it binds most

PHE 2, THR 2, ALA 2, ILE 2, LEU 2, ARG 2, GLU 2, GLY 2, MET 2, TRP 2 (residue and the binding sites it lines).

Found with

  • HEM · Protoporphyrin IX containing Fe
  • EDO · 1,2-ethanediol
  • GOL · Glycerol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.