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Ligand · 0H4

0H4 · (2S)-3-cyclopentyl-N-(5-methylpyridin-2-yl)-2-[2-oxo-4-(trifluoromethyl)pyridin-1(2H)-yl]propanamide

0H4, (2S)-3-cyclopentyl-N-(5-methylpyridin-2-yl)-2-[2-oxo-4-(trifluoromethyl)pyridin-1(2H)-yl]propanamide (C20 H22 F3 N3 O2, 393.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
0H4
Formula
C20 H22 F3 N3 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

0H4 in 2 structures; the first of them:

  • 3VEV · Glucokinase in complex with an activator and glucose · 0H4 A502 · binds TYR61, VAL62, ARG63, SER64, THR65, PRO66, ILE159, MET210 and 10 more
  • 3VEV · Glucokinase in complex with an activator and glucose · 0H4 A502 · binds TYR61, VAL62, ARG63, SER64, THR65, PRO66, ILE159, MET210 and 10 more

Residues it binds most

TYR 2, VAL 2, ILE 2, MET 2, ALA 2, ARG 2, CYS 2, HIS 2, LEU 2, PRO 2 (residue and the binding sites it lines).

Found with

  • NA · Sodium ion
  • GLC · alpha-D-glucopyranose

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