Ligand · 0F4
0F4 · 1-(3-{[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-2,3-dihydro-1H-indol-6-yl]amino}phenyl)-3-[3-(trifluoromethyl)phenyl]urea
0F4, 1-(3-{[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-2,3-dihydro-1H-indol-6-yl]amino}phenyl)-3-[3-(trifluoromethyl)phenyl]urea (C27 H20 F3 N5 O2, 503.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…
- Component
- 0F4
- Formula
- C27 H20 F3 N5 O2
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
0F4 in 2 structures; the first of them:
- 3V5Q · Discovery of a selective TRK Inhibitor with efficacy in rodent cancer tumor models · 0F4 A902 · binds LEU544, VAL552, ALA570, LYS572, GLU588, LEU591, LEU592, LEU595 and 17 more
- 3V5Q · Discovery of a selective trk inhibitor with efficacy in rodent cancer tumor models · 0F4 A902 · binds LEU544, VAL552, ALA570, LYS572, GLU588, LEU591, LEU592, LEU595 and 17 more
Residues it binds most
LEU 4, PHE 4, GLU 4, GLY 4, ILE 4, LYS 4, VAL 4, HIS 4, ALA 4, ASP 4 (residue and the binding sites it lines).
Found with
- CL · Chloride ion
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