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Ligand · 0CV

0CV · 6-methoxy-3,8-dimethyl-4-(piperazin-1-yl)-1H-pyrazolo[3,4-b]quinoline

0CV, 6-methoxy-3,8-dimethyl-4-(piperazin-1-yl)-1H-pyrazolo[3,4-b]quinoline (C17 H21 N5 O, 311.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
0CV
Formula
C17 H21 N5 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

0CV in 2 structures; the first of them:

  • 3UUO · The discovery of potent, selectivity, and orally bioavailable pyrozoloquinolines as PDE10… · 0CV A1 · binds TYR524, LEU635, LEU675, SER677, VAL678, ILE692, TYR693, PHE696 and 4 more
  • 3UUO · The discovery of potent, selectivity, and orally bioavailable pyrozoloquinolines as PDE10… · 0CV A1 · binds TYR524, LEU635, LEU675, SER677, VAL678, ILE692, TYR693, PHE696 and 4 more

Residues it binds most

LEU 4, PHE 4, TYR 4, GLN 4, GLY 4, ILE 4, MET 4, SER 4, VAL 4, HIS 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion
  • PO4 · Phosphate ion

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