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Ligand · 0C8

0C8 · 4-[(4-{[2-(trifluoromethoxy)phenyl]amino}pyrimidin-2-yl)amino]benzoic acid

0C8, 4-[(4-{[2-(trifluoromethoxy)phenyl]amino}pyrimidin-2-yl)amino]benzoic acid (C18 H13 F3 N4 O3, 390.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component
0C8
Formula
C18 H13 F3 N4 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

0C8 in 2 structures; the first of them:

  • 3UP2 · Aurora A in complex with RPM1686 · 0C8 A1 · binds ARG137, LEU139, GLY140, LYS141, VAL147, ALA160, LEU194, GLU211 and 11 more
  • 3UP2 · Aurora a in complex with RPM1686 · 0C8 A1 · binds ARG137, LEU139, GLY140, LYS141, VAL147, ALA160, LEU194, GLU211 and 11 more

Residues it binds most

ALA 2, LEU 2, ARG 2, GLU 2, GLY 2, ASN 2, ASP 2, LYS 2, PRO 2, THR 2 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

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