GL1X · GenesisL1 explorer

Ligand · 06H

06H · (6S)-4,6,15,15,18-pentamethyl-5,17-dioxo-2,3,4,5,6,7,14,15,16,17-decahydro-1H-12,8-(metheno)[1,4,9]triazacyclotetradecino[9,8-a]indole-9-carboxamide

06H, (6S)-4,6,15,15,18-pentamethyl-5,17-dioxo-2,3,4,5,6,7,14,15,16,17-decahydro-1H-12,8-(metheno)[1,4,9]triazacyclotetradecino[9,8-a]indole-9-carboxamide (C25 H32 N4 O3, 436.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2…

Component
06H
Formula
C25 H32 N4 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

06H in 2 structures; the first of them:

  • 3R91 · Macrocyclic lactams as potent Hsp90 inhibitors with excellent tumor exposure and extended… · 06H A1 · binds ASN51, SER52, ASP54, ALA55, LYS58, ASP93, ILE96, GLY97 and 12 more
  • 3R91 · Macrocyclic lactams as potent HSP90 inhibitors with excellent tumor exposure and extended… · 06H A1 · binds ASN51, SER52, ASP54, ALA55, LYS58, ASP93, ILE96, GLY97 and 12 more

Residues it binds most

ASP 2, GLY 2, ALA 2, LEU 2, ASN 2, ILE 2, LYS 2, MET 2, PHE 2, SER 2 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.