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Ligand · 04K

04K · 2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-6-(4-fluorophenoxy)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one

04K, 2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-6-(4-fluorophenoxy)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one (C26 H28 F N5 O3, 477.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with…

Component
04K
Formula
C26 H28 F N5 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

04K in 2 structures; the first of them:

  • 3PJ2 · Crystal structure of BTK kinase domain complexed with… · 04K A1 · binds GLU407, LEU408, VAL416, ALA428, LYS430, MET449, VAL458, THR474 and 9 more
  • 3PJ2 · Crystal structure of btk kinase domain complexed with 2-[4-(2… · 04K A1 · binds GLU407, LEU408, VAL416, ALA428, LYS430, MET449, VAL458, THR474 and 9 more

Residues it binds most

ALA 2, GLU 2, LEU 2, MET 2, VAL 2, ASP 2, GLY 2, LYS 2, PHE 2, SER 2 (residue and the binding sites it lines).

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